Brain Tumour Pathway – a REDCap Project

  Critical to accelerating the discovery of new therapies for brain tumours and their translation into the clinic, is to investigate diagnosis, treatment and outcomes at a population level, mapping this to molecular interrogation of resected tumour tissue, and liquid biopsies from patients. In collaboration with researchers at the Scotland CRUK centre, Paul has curated a uniquely granular data set of >1500 patients diagnosed with brain tumours. This intersects with Edinburgh’s CRUK Glioma genetic and cellular resource of human cells lines, as well as other large scale omics analysis of patient subsets. With this data we are better understanding tumour diagnosis, treatment efficacy and patient outcome, feeding the data back into discovery science and clinical trial design.  

  Dr Paul Brennan is Reader, Honorary Consultant Neurosurgeon and Clinical Director at the University of Edinburgh and NHS Lothian. His research spans the laboratory and the clinic, combining molecular, epidemiology and clinical investigation to guide rationale innovation to improve patient care.

  The Edinburgh Cancer Information team is supporting him in the development, completion and constant improvement of the database to a high standard, to improve research and patient care for those with brain cancer.